Commentary on Immune System Associated Diseases Caused by Viruses: The Role of EBV
نویسندگان
چکیده
RefeRences Yuling, H., Ruijing, X., Li, L., Xiang, J., Rui, Z., Yujuan, W., Lijun, Z., Chunxian, D., Xinti, T., Wei, X., Lang, C., Yanping, J., Tao, X., Mengjun, W., Jie, X., Youxin, J., and Jinquan, T. (2009). EBV-induced human CD8 NKT cells suppress tumorigenesis by EBV associated malignancies. Cancer Res. 69, 7935–7944. Serafini, B., Rosicarelli, B., Franciotta, D., Magliozzi, R., Reynolds, R., Cinque, P., Andreoni, L., Trivedi, P., Salvetti, M., Faggioni, A., and Aloisi, F. (2007). Dysregulated Epstein–Barr virus infection in the multiple sclerosis brain. J. Exp. Med. 204, 2899–2912.
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Epstein–Barr Virus, the Immune System, and Associated Diseases
Host immune system is designed (or evolved) to fight against different pathogens. Many viruses infect the immune cells for the propagation of new progenies, thus the infection may modulate the host immune homeostasis. It has been more than 45 years since the discovery of Epstein-Barr virus (EBV) from a Burkitt's lymphoma derived cell line. The ability of EBV to transform primary B cells in vitr...
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